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Tatiana Akimova
Scientist II

I am from Russia, where I received MDs in Family Medicine and Immunology and Allergy and completed PhD work on type I Diabetes and Polyglandular autoimmune syndromes. During my clinical residency and PhD scholarship, I worked in a clinical immunology lab, focusing on autoimmune diagnostics. In 2009, I joined Dr. Hancock’s lab as a postdoctoral fellow to study epigenetic regulation of FOXP3+ regulatory T cells (Tregs). While others in the lab work in murine models, my research interest concentrates upon the biology of human Tregs in clinical samples. My ongoing projects involve studies of Tregs and T cells in i) organ transplantation, ii) cancer, iii) obesity, iv) sarcoidosis, and vi) last, but not least, the epigenetic regulation of Treg phenotype and function.

Research

  • Histone/protein Deacetylases
    HDAC-e1502818213336
  • Histone/protein Acetyltransferases
  • Deubiquitinases
  • Transplantation
  • Tumor Immunology
  • Ischemia/reperfusion Injury
  • Immunometabolism

Hancock Lab

University of Pennsylvania School of Medicine
916B Abramson Research Center
3615 Civic Center Boulevard
Philadelphia, PA 19104
(215) 590-8709

Funding

National Institutes of Health (NIAID, NCI, NIDDK)
Department of Defense
Fred and Suzanne Biesecker Pediatric Liver Center

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Link to: Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function Link to: Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function Link to: Turning on Pro-Repair Cells in the Lungs Link to: Turning on Pro-Repair Cells in the Lungs Turning on Pro-Repair Cells in the Lungs
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