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Regulatory T Cells: Gene Expression and Gene Suppression
American Journal of Transplantation
Human lung tumor FOXP3+ Tregs upregulate four “Treg-locking” transcription factors
This paper from Tatiana Akimova and colleagues involved several years of work and is both a technical tour-de-force and a stellar contribution. Basically, Dr. Akimova isolated Tregs from within tumors of patients with lung cancer and compared their properties with Tregs from the blood, lymph node and lungs of these patients. Compared to the other Treg populations, tumor Tregs were […]
Hancock Lab
University of Pennsylvania School of Medicine
916B Abramson Research Center
3615 Civic Center Boulevard
Philadelphia, PA 19104
(215) 590-8709