Entries by awp-admin

Turning on Pro-Repair Cells in the Lungs

Turning on Pro-Repair Cells in the Lungs
Franco R. D’Alessio, MD, Assistant Professor of Medicine, Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine
8 November 2017 | 2:00 pm – 3:00 pm | Buerger Building Room 1214-CR3

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function

A visiting scholar from Shanghai, Dr. Jianbing Huang, along with our own mighty Liqing Wang, studied the effects of genetic and pharmacologic targeting of Hdac11 in mice. Deletion of Hdac11 in Foxp3+ Tregs, or its pharmacologic inhibition, enhanced Treg function and promoted cardiac allograft survival. This work highlights the potential importance of a little studied Hdac in the development […]